TL;DR: Poorly. Not recommended!
If you want to delve into the details, read this. (The main problems are that it uses some made up relative terms and then combines them in a way that is illogical.)
If you’ve already started using the made up relative terms that SAFe suggests, all is not lost. At least make sure you combine them in a more sensible way. (That should avoid the worst of the nonsense results.)
If Value =0, or urgency = 0, then of course, the Cost of Delay should be zero. If it’s not, you can be pretty sure you’ve combined your made-up terms in a way that doesn’t make sense. Might want to fix that!
If you haven’t started, and you’re afraid of quantifying Cost of Delay, then you could try this qualitative approach – at least to do a quick scan of options. If you’re feeling brave, you could then have a go at quantifying the Cost of Delay for a few options that you think are the highest value and urgency.
Doing that will start to show you the highly non-linear distribution of value. This doesn’t show up though until you do the slightly hard work of quantifying value and urgency.
Don’t stop there though. To get to a suggested order for your options you’re going to need to divide by the blocking time = “Duration”. That give you CD3. Here’s how that works at scale.
Hopefully that helps!